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Clozaril uses: used to treat schizophrenia in patients where other medicine has not worked. Clozapine is in a class of medications called antipsychotics. It works by decreasing abnormal excitement in the brain.

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. .Used to treat schizophrenia in patients where other medicine has not worked. .Used to treat schizophrenia in patients where other medicine has not worked. .used to treat schizophrenia in patients where other medicine has not worked. Clozapine is in a class of medications called antipsychotics. It works by decreasing abnormal excitement in the brain. . . . . . .Clozapine is an anti-psychotic medication that works by blocking receptors in the brain for several neurotransmitters (chemicals that nerves use to communicate with each other) including dopamine type 4 receptors, serotonin type 2 receptors, norepinephrine receptors, acetylcholine receptors, and histamine receptors. Unlike traditional anti-psychotic agents, such as chlorpromazine (Thorazine) and haloperidol (Haldol) as well as the newer anti-psychotics, risperidone (Risperdal) and olanzapine (Zyprexa), clozapine only weakly blocks dopamine type 2 receptors. Clozapine is use in the management of psychotic disorders including schizophrenia. Because of concern for the side effect of agranulocytosis (see side effects), clozapine should be reserved for patients who have failed to respond to other standard medications or who are at risk for recurring suicidal behavior. . .
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