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.Imipramine is used to elevate the mood of patients with depression. Imipramine also causes sedation. Therefore, it is useful in depressed patients with insomnia, restlessness, and nervousness. Imipramine is an antidepressant medication of the tricyclic class. Medications in this class are often referred to as tricyclic antidepressants or TCAs. Depression is defined as an all-pervasive sense of sadness and gloom. In patients with depression, abnormal levels of chemicals in the brain (called neurotransmitters) may be the cause of their depression. These neurotransmitters are what the nerves in the brain use to communicate with each other. Imipramine elevates mood by raising the level of neurotransmitters in brain tissue. Imipramine also is used for childhood enuresis (bedwetting), several disorders associated with chronic pain, and attention-deficit hyperactivity disorder (ADHD. . . . . . .
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